About the lab

The Alvarez-Buylla Lab is an academic neuroscience research laboratory.  The lab is part of the University of California, San Francisco and is housed inside the Ray and Dagmar Dolby Regenerative Medicine building.

 

 

Index

  1. General
  2. Lab History
  3. Lab Features
  4. Lab Funding

 

 

General Back to page index

 

Current number of post-doctorate scholars

3

Current number of graduate students

1

Current number of staff

3

Lab alumni with their own laboratory

Carlos Lois (Caltech)

Daniel Lim (UCSF)

Joanne Conover (University of Connecticut)

Fiona Doetsch 

Nader Sanai (Barrow Neurlogical Institute)

Alfred Quinones-Hinojosa (Johns Hopkins University)

Leopoldo Petreanu (Champalimaud Foundation, Portugal)

Rebecca Ihrie (Vanderbilt University)

Young-Goo Han (St. Jude's Hospital)

Minoree Kohwi (Columbia University)

Hirohide Takebayashi (Niigata University, Japan)

Kazunobu Sawamoto (Nagoya City University, Japan)

Nathalie Spassky (Institut de Biologie de l’Ecole Normale Supérieure)

Hynek Wichterle (Columbia University)

Matthew Tate (Northwestern University)

Mercedes Paredes (UCSF)

Shawn Sorrells (University of Pittsburgh)

Derek Southwell (Duke University)

 

 

 

Lab History Back to page index

 

Arturo Alvarez-Buylla started his laboratory in 1989 at Rockefeller University, New York.  The lab received its first NIH grant in in 1990 (NS28478) to study the origin of new neurons in the audlt avian brain.

 

Arturo Alvarez-Buylla (left) and Carlos Lois (right).

 

Arturo in his old office at Rockefeller (right).

 

Arturo's last days at Rockefeller.

 

The laboratory moved across the country in the year 2000 to the University of California, San Francisco (UCSF).  The new home of the laboratory was in the Health Sciences West building on the Parnassus campus. 

 

UCSF Health Sciences West Building

 

UCSF finishd construction of the Ray and Dagmar Dolby Building in 2011 and soon after, the laboratory moved into its new (and current) home.  For details about the building, consult this article from Archdaily.com.

 

View of the regen. med. building from the service roadView of the Regen. Med. building from the forest

The Regenerative Medicine Building (above, gray with green roof) is located on the edge of the UCSF Parnassus Campus next to the Mt. Sutro Open Space Preseve.

  

 

 

Lab Features Back to page index

The Alvarez-Buylla laboratory is equipped for molecular biology, surgery, histology, microscopy, and cell culture work.  The lab has a workbench for fabricating and cutomizing parts.

Our microscopy work is performed with our Leica SP8 white-light laser inverted confocal, two standard fluorescent microscopes, three stereo dissection microscopes, and a computer-microscope mapping and morphometry system. 

The lab's molecular biology equipment includes two thermal cyclers, gel electrophoresis rigs and power supplies, and shaking incubators (shared). 

Our surgical equipment includes; dissection microscopes, biological safety cabinets (shared), sonication water baths, custom desinged and built stereotaxic injection apparatuses, and access to two surgical suites for survival surgeries. 

The histological equipment consists of a vibratome, sliding microtome, ultra microtome, and a cryostat. We conduct cell and tissue culture work using three CO2 incubators, two biological safety cabinets, and a centrifuge. 

Our microscopy work is performed with our Leica SP8 white-light laser inverted confocal, two standard fluorescent microscopes, three stereo dissection microscopes, and a computer-microscope mapping and morphometry system. 

For general lab use, we have two liquid nitrogen freezers, two -80 Celsius freezers, two -20 Celsius freezers, 5 mini-fridges, three full-size fridges, autoclave services, and glassware cleaning service.

In addition to these amenities, UCSF provides access to cell sorting, confocal microscopy, and electron microscopy core facilities on a rental basis.

Our microscope room.

 

 

 

Reagent preparation and histology area.

 

Vented perfusion hood

Dedicated and vented perfusion hood.

 

 

 

Lab Funding Back to page index

This Alvarez-Buylla laboratory is sponsored by four grants from the National Institutes of Health (R01 NS113910, R01 NS28478, R01 MH122478, and P01 NS083513), and a generous gift from the JG Bowes Foundation.